O-DSMT (O-Desmethyltramadol)

O-DSMT (O-Desmethyltramadol) (3-[(1R,2R)-2-[(dimethylamino)methyl]-1-hydroxycyclohexyl]phenol) is a reference compound belonging to the Arylcyclohexylamines class, characterized by the molecular formula C15H23NO2 and a molar mass of 249.35 g/mol. The parent molecule is indexed under CAS registry number 80456-81-1 and in the NCBI PubChem database as CID 9838803 (Standard InChIKey: UWJUQVWARXYRCG-HIFRSBDPSA-N).

In documented chemical and harm-reduction literature (PubChem / PsychonautWiki, CC BY 4.0), O-DSMT (O-Desmethyltramadol) is indexed within the Phenylpropylamine structural group. Toxicological notes (PsychonautWiki): moderate potential toxicity relative to its dose due to its potency, potentially lethal when mixed with depressants like alcohol or benzodiazepines. Dependence liability (PsychonautWiki): moderately addictive with a high potential for abuse. Documented cross-tolerance class: opioids. Standard laboratory handling precautions—including nitrile gloves, eye protection, and local exhaust ventilation—apply whenever handling the reference material.

This reference sheet provides chemical, analytical, and toxicological provenance only. The material is strictly not for human consumption, diagnostic, or veterinary use. Research-use labelling does not establish legal status in any jurisdiction.